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Elevated Fasting Serum Gastrin: Sensitivity and Specificity

Introduction: None written. Excerpt from the entry in Zollinger-Ellison syndrome:
above upper limit of normal. No specificity mentioned but 2/3 of patients have elevated fasting gastrin < 10x upper limit, which overlaps with H pylori or G cell hyperplasia.

Also must ensure that gastric pH is normal for this test to be valid.

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Associated Diagnoses:

Zollinger-Ellison syndrome

97% sensitive

Pernicious Anemia

90% sensitive