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Sensitive and Specific Findings

Specific Findings

Sensitive Findings

Takayasu's Arteritis: Sensitivity and Specificity

Introduction: also known as Pulseless Disease.

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Tags: Inflammatory Vascular Vasculitis Tag this Diagnosis.

The sensitivity and specificity of findings for Takayasu's Arteritis are listed below. See the left navigation bar to change the display.

Sensitive and Specific Findings

Finding SensitivitySpecificity Comments, Study
CT angiography Edit 95%100%

in patients suspected of having Takayasu's

Study: Radiology. 1998 Oct;209(1):103-9. PMID 9769819

ACR Criteria Edit 90.5%97.8%

>=3/6 criteria:

  • Age at disease onset ≤40 years
  • Claudication of the extremities
  • Decreased pulsation of one or both brachial arteries
  • Difference of at least 10 mmHg in systolic blood pressure between the arms
  • Bruit over one or both subclavian arteries or the abdominal aorta
  • Arteriographic narrowing or occlusion of the entire aorta, its primary branches, or large arteries in the proximal upper or lower extremities, not due to arteriosclerosis, fibromuscular dysplasia, or other causes
  • Study: Arthritis Rheum 1990 Aug;33(8):1129-34. PMID 1975175

    Specific Findings

    Finding SensitivitySpecificity Comments, Study
    Ultrasound Edit 55%94%

    halo sign on Ultrasound. Gold standard was ACR criteria (for gold standard of biopsy, sens=69%/spec=82%). Stenosis or occlusion had similar sensitivities to halo sign.

    Study: Ann Intern Med. 2005 Mar 1;142(5):359-69 PMID 15738455

    Sensitive Findings

    Finding SensitivitySpecificity Comments, Study
    Gender Edit Sensitivity = 85%

    85% of those affected are women. Onset is usually <20, or more broadly 10-40 years of age. Prevalence is far greater in Asians.

    Study: Am Heart J 1977 Jan;93(1):94-103. PMID 12655