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Specific Findings

Sensitive Findings

Spontaneous Bacterial Peritonitis: Sensitivity and Specificity

Introduction: This diagnosis carries a high mortality rate, around 30%. Diagnostic paracentesis is critical in the diagnosis (and may be therapeutic in non-infective ascites).

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Tags: Hepatic Infection Tag this Diagnosis.

Prevalence

Population / CalculatorPrevalence Comments / Study / Link
Cirrhosis patients admitted to the hospital 27% JAMA. 2008;299(10):1166-1178. http://jama.ama-assn.org/cgi/content/full/299/10/1166
Cirrhosis patients with prior SBP 0% Much higher prevalence - these patients are placed on prophylactic antibiotics.
Cirrhosis patients with low ascitic protein 0% Much higher. These patients get prophylactic antibiotics.
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The sensitivity and specificity of findings for Spontaneous Bacterial Peritonitis are listed below. See the left navigation bar to change the display.

Sensitive and Specific Findings

Finding SensitivitySpecificity Comments, Study
Ascitic Fluid PMN Edit 85%92%

>500/ul

Study: JAMA. 2008;299(10):1166-1178. http://jama.ama-assn.org/cgi/content/full/299/10/1166

Specific Findings

Finding SensitivitySpecificity Comments, Study
Ascitic Fluid WBC Edit 77%92%

>1000/ul

Study: JAMA. 2008;299(10):1166-1178. http://jama.ama-assn.org/cgi/content/full/299/10/1166

Ascitic Fluid pH Edit 71%92%

<7.35

Study: JAMA. 2008;299(10):1166-1178. http://jama.ama-assn.org/cgi/content/full/299/10/1166

Blood-Ascites pH Gradient Edit 73%90%

>0.10

Study: JAMA. 2008;299(10):1166-1178. http://jama.ama-assn.org/cgi/content/full/299/10/1166

Sensitive Findings

Finding SensitivitySpecificity Comments, Study
Serum-Ascites Albumin Gradient Edit 95%79%

>=1.1g/dl

Study: JAMA. 2008;299(10):1166-1178. http://jama.ama-assn.org/cgi/content/full/299/10/1166