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Spinal Discitis and Osteomyelitis: Sensitivity and Specificity

Introduction: Infection of the vertebral bodies, centered at the intervertebral disc. The infection often spreads to the prevertebral soft tissues and into the epidural space. It most commonly affects the lumbar spine.

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Tags: Infection Neurologic Tag this Diagnosis.

The sensitivity and specificity of findings for Spinal Discitis and Osteomyelitis are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %. Post-Test Probability (Predictive Value): %. Switch to display mode.
**Note that calculating probabilities from more than one finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)
Sensitive and Specific Findings
FindingResult SensitivitySpecificity
[ + ] Gallium WBC Scan and Bone Scan + 0 - 90%100%
[ + ] MRI + 0 - 96%92%
[ + ] Tc99m Bone Scan + 0 - 87%91%
Sensitive Findings
FindingResult SensitivitySpecificity
[ + ] Elevated CRP Sensitivity = 100%
[ + ] Localized Pain Sensitivity = 95%
Poorly Diagnostic Findings
FindingResult SensitivitySpecificity
[ + ] Spine X-Ray + 0 - 82%57%
[ + ] Elevated ESR Sensitivity = 80%
[ + ] Blood Cultures Sensitivity = 56%
[ + ] Focal Neurological Signs Sensitivity = 40%
[ + ] Leukocytosis Sensitivity = 40%