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Septic Arthritis: Sensitivity and Specificity

Introduction: None written.

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Tags: Infection Tag this Diagnosis.

Prevalence

Population / CalculatorPrevalence Comments / Study / Link
Patients presenting with acute monoarthritis 8% Another study reported 27%.

JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478

More, Edit...

The sensitivity and specificity of findings for Septic Arthritis are listed below. See the left navigation bar to change the display.

Specific Findings

Finding SensitivitySpecificity Comments, Study
Synovial WBC
Duplicate Edit
29%99%

>100k

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478

Recent Joint Surgery Edit 24%96%

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478

Diabetes Edit 12%96%

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478

Age Edit 19%95%

>80 years

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478

Synovial WBC
Duplicate Edit
62%92%

>50k

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478

Joint Prosthesis Edit 35%89%

for hip or knee

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478

Skin infection Edit 32%88%

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478

Synovial Glucose Edit 51%85%

Low, defined differently in different studies.

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478

Sensitive Findings

Finding SensitivitySpecificity Comments, Study
Synovial LDH Edit 100%51%

>250 U/L

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478

Elevated ESR Edit 95%29%

>30mm/hr

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478

Leukocytosis Edit 90%36%

>10,000/ul

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478

Pain in Joint Edit Sensitivity = 85%

specificity not evaluated

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478

Negative Findings

Finding SensitivitySpecificity Comments, Study
Synovial Protein Edit 48%46%

>3g/dl

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478

Fever Edit 46%31%

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478/JRC70001T2

Poorly Diagnostic Findings

Finding SensitivitySpecificity Comments, Study
Synovial PMN Edit 73%79%

>90%

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478/JRC70001T2

Rheumatoid Arthritis Edit 68%73%

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478/JRC70001T2

Elevated CRP Edit 77%53%

>100mg/l

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478/JRC70001T2

History of HIV Edit 79%50%

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478/JRC70001T2

Joint Edema Edit Sensitivity = 78%

specificity not assessed

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478/JRC70001T2