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Septic Arthritis: Sensitivity and Specificity

Introduction: None written.

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Prevalence

Population / Calculator	Prevalence	Comments / Study / Link
Patients presenting with acute monoarthritis	8%	Another study reported 27%. JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
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The sensitivity and specificity of findings for Septic Arthritis are listed below. See the left navigation bar to change the display.

Blood Test

Finding	Sensitivity	Specificity	Comments, Study
Elevated CRP	77%	53%	>100mg/l Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478/JRC70001T2
Elevated ESR	95%	29%	>30mm/hr Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
Leukocytosis	90%	36%	>10,000/ul Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478

Fluid Test

Finding	Sensitivity	Specificity	Comments, Study
Synovial Glucose	51%	85%	Low, defined differently in different studies. Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
Synovial LDH	100%	51%	>250 U/L Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
Synovial PMN	73%	79%	>90% Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478/JRC70001T2
Synovial Protein	48%	46%	>3g/dl Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
Synovial WBC Duplicate	29%	99%	>100k Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
Synovial WBC Duplicate	62%	92%	>50k Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478

History

Finding	Sensitivity	Specificity	Comments, Study
Age	19%	95%	>80 years Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
Diabetes	12%	96%	Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
History of HIV	79%	50%	Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478/JRC70001T2
Joint Prosthesis	35%	89%	for hip or knee Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
Pain in Joint	Sensitivity = 85%		specificity not evaluated Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
Recent Joint Surgery	24%	96%	Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
Rheumatoid Arthritis	68%	73%	Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478/JRC70001T2

Physical Exam

46%

31%

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478/JRC70001T2

Sensitivity = 78%

specificity not assessed

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478/JRC70001T2

Renal

46%

31%

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478/JRC70001T2

Vital Signs

46%

31%

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478/JRC70001T2

Untagged

32%

88%

Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478