Sepsis: Sensitivity and Specificity

Introduction: Sepsis is a systemic inflammatory response (SIRS) due to a known or presumed infection. Various serologic markers have been proposed to distinguish sepsis from SIRS due to other causes. See also Mortality in Sepsis (has definitions in that intro).

[Edit Diagnosis] [Merge dx] [Add prevalence]

Tags: Infection Tag this Diagnosis.

The sensitivity and specificity of findings for Sepsis are listed below. See the left navigation bar to change the display.

Sensitive and Specific Findings

Finding	Sensitivity	Specificity	Comments, Study
TREM-1	96%	89%	ICU pts with clinically suspected infection and >=2 criteria of SIRS Study: Ann Intern Med 2004 Jul 6;141(1):9-15. PMID 15238365

Poorly Diagnostic Findings

Finding	Sensitivity	Specificity	Comments, Study
Elevated Procalcitonin	71%	71%	Study: Lancet Infect Dis. 2007 Mar;7(3):210-7. PMID 17317602