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Sepsis: Sensitivity and Specificity

Introduction: Sepsis is a systemic inflammatory response (SIRS) due to a known or presumed infection. Various serologic markers have been proposed to distinguish sepsis from SIRS due to other causes. See also Mortality in Sepsis (has definitions in that intro).

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Tags: Infection Tag this Diagnosis.

The sensitivity and specificity of findings for Sepsis are listed below. See the left navigation bar to change the display.

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Finding SensitivitySpecificity Comments, Study
Elevated Procalcitonin Edit 71%71%

Study: Lancet Infect Dis. 2007 Mar;7(3):210-7. PMID 17317602

TREM-1 Edit 96%89%

ICU pts with clinically suspected infection and >=2 criteria of SIRS

Study: Ann Intern Med 2004 Jul 6;141(1):9-15. PMID 15238365