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Specific Findings

Pemphigus Vulgaris: Sensitivity and Specificity

Introduction: None written.

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Tags: Dermatologic Tag this Diagnosis.

The sensitivity and specificity of findings for Pemphigus Vulgaris are listed below. See the left navigation bar to change the display.

Specific Findings

Finding SensitivitySpecificity Comments, Study
Nikolskiy Sign
Duplicate Edit		 38%100%

"Direct": an attempt to induce the erosion by pressure applied as described above (rubbing the skin with a twisting motion with the thumb) to normal-appearing areas of skin distant from the lesions

Study: J Am Acad Dermatol. 2006 Mar;54(3):411-5. PMID: 16488290
Nikolskiy Sign
Duplicate Edit		 69%94%

"Marginal": an attempt to extend the erosion to the surrounding normal-appearing skin by pulling the remnant of the blister wall or rubbing the skin with a twisting motion with the thumb to avoid applying strong shearing force at the periphery of existing lesions

Study: J Am Acad Dermatol. 2006 Mar;54(3):411-5. PMID: 16488290

 

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