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Pemphigus Vulgaris: Sensitivity and Specificity

Introduction: None written.

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Tags: Dermatologic Tag this Diagnosis.

The sensitivity and specificity of findings for Pemphigus Vulgaris are listed below. See the left navigation bar to change the display.

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Finding SensitivitySpecificity Comments, Study
Nikolskiy Sign
Duplicate Edit		 69%94%

"Marginal": an attempt to extend the erosion to the surrounding normal-appearing skin by pulling the remnant of the blister wall or rubbing the skin with a twisting motion with the thumb to avoid applying strong shearing force at the periphery of existing lesions

Study: J Am Acad Dermatol. 2006 Mar;54(3):411-5. PMID: 16488290
Nikolskiy Sign
Duplicate Edit		 38%100%

"Direct": an attempt to induce the erosion by pressure applied as described above (rubbing the skin with a twisting motion with the thumb) to normal-appearing areas of skin distant from the lesions

Study: J Am Acad Dermatol. 2006 Mar;54(3):411-5. PMID: 16488290

 

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