Neuromyelitis Optica: Sensitivity and Specificity
Introduction: also known as Devic Disease. It is usually viewed as a subtype of multiple sclerosis only involving the optic nerve and cervical spinal cord. Most cases are relapsing, and the initial presentation may involve only one component of the syndrome.
Revised diagnostic criteria for NMO published in 2006 require optic neuritis, myelitis, and at least two of three supportive criteria:
* A contiguous spinal cord lesion on MRI extending three or more segments
* Initial brain MRI not meeting usual diagnostic criteria for MS
* Seropositivity for NMO-IgG