Idiopathic Pulmonary Fibrosis: Sensitivity and Specificity

Introduction: also known as Fibrosing Alveolitis (in older literature), it is one type of Interstitial Lung Disease.

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The sensitivity and specificity of findings for Idiopathic Pulmonary Fibrosis are listed below. See the left navigation bar to change the display.

Specific Findings

Finding	Sensitivity	Specificity	Comments, Study
Clinical diagnosis	62%	97%	Clinical diagnosis includes: history, HRCT, and bronchoscopy (gold standard is lung biopsy). Community patients referred for further definitive diagnostic evaluation of new-onset, untreated nonspecific ILD. Study: Chest. 1999 Nov;116(5):1168-74. PMID: 10559072
High-Resolution Chest CT (HRCT)	78.5%	90%	Community patients referred for further definitive diagnostic evaluation of new-onset, untreated nonspecific ILD. Another study found 88% sensitivity (Chest. 1995 Jul;108(1):109-15. PMID: 7606943). Study: Chest. 1999 Nov;116(5):1168-74. PMID: 10559072