Idiopathic Pulmonary Fibrosis: Sensitivity and Specificity

Introduction: also known as Fibrosing Alveolitis (in older literature), it is one type of Interstitial Lung Disease.

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The sensitivity and specificity of findings for Idiopathic Pulmonary Fibrosis are listed below. See the left navigation bar to change the display.

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Finding	Sensitivity	Specificity	Comments, Study
Clinical diagnosis	62%	97%	Clinical diagnosis includes: history, HRCT, and bronchoscopy (gold standard is lung biopsy). Community patients referred for further definitive diagnostic evaluation of new-onset, untreated nonspecific ILD. Study: Chest. 1999 Nov;116(5):1168-74. PMID: 10559072
High-Resolution Chest CT (HRCT)	78.5%	90%	Community patients referred for further definitive diagnostic evaluation of new-onset, untreated nonspecific ILD. Another study found 88% sensitivity (Chest. 1995 Jul;108(1):109-15. PMID: 7606943). Study: Chest. 1999 Nov;116(5):1168-74. PMID: 10559072