Diabetes Mellitus: Sensitivity and Specificity

Introduction:

See also Insulin Resistance. The gold standard for diabetes is the Oral Glucose Tolerance Test (OGTT), where blood glucose levels are measured at specified time intervals after a specified oral glucose load.

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The sensitivity and specificity of findings for Diabetes Mellitus are listed below. See the left navigation bar to change the display.

Specific Findings

Finding	Sensitivity	Specificity	Comments, Study
Fasting Plasma Glucose	56%	96%	>110mg/dl Study: Diabet Med. 2007 Apr;24(4):333-43. PMID: 17367307
HbA1c Duplicate	60%	95%	>=6.2% Study: Diabet Med. 2007 Apr;24(4):333-43. PMID: 17367307
Elevated ESR	68%	94%	> 70mm/hr. population: diabetics Study: JAMA. 2008;299(7):806-813. http://jama.ama-assn.org/cgi/content/full/299/7/806
Ulcer > 2cm	56%	92%	population: diabetics Study: JAMA. 2008;299(7):806-813. http://jama.ama-assn.org/cgi/content/full/299/7/806
Probe to Bone	65%	90%	population: diabetics Study: JAMA. 2008;299(7):806-813. http://jama.ama-assn.org/cgi/content/full/299/7/806

Sensitive Findings

Finding	Sensitivity	Specificity	Comments, Study
MRI	89%	77%	population: diabetics Study: JAMA. 2008;299(7):806-813. http://jama.ama-assn.org/cgi/content/full/299/7/806

Poorly Diagnostic Findings

Finding	Sensitivity	Specificity	Comments, Study
HbA1c Duplicate	80%	82%	>=6.1% Study: Diabet Med. 2007 Apr;24(4):333-43. PMID: 17367307
Plain X-Ray	51%	78%	population: diabetics Study: JAMA. 2008;299(7):806-813. http://jama.ama-assn.org/cgi/content/full/299/7/806