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Acute Conjunctivitis, Bacterial: Sensitivity and Specificity

Introduction: Acute conjunctivitis can be either viral or bacterial. One study in children had a 54% prevalence of bacterial etiology (42% H flu, 12% S pneumo) and 20% prevalence of adenoviral, with ~30% culture negative [J Pediatr. 1981 Apr;98(4):531-6. PMID: 6970802]. Another study in adults showed that 32% of patients had a bacterial etiology, with 47% S pneumo, 23% S aureus, 16% H flu [BMJ. 2004 Jul 24;329(7459):206-10. PMID: 1520119].

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Tags: Infection Ophthalmology Tag this Diagnosis.

The sensitivity and specificity of findings for Acute Conjunctivitis, Bacterial are listed below. See the left navigation bar to change the display.

Specific Findings

Bilateral Glued Eyes

40%

89%

in the morning

Study: BMJ. 2004 Jul 24;329(7459):206-10. PMID: 15201195. [Note that I have recalculated the PLR and NLR from their raw data - I disagree with the way they calculated certain things.]

Sensitive Findings

92%

27%

either unilateral or bilateral, in the morning

Study: BMJ. 2004 Jul 24;329(7459):206-10. PMID: 15201195. [Note that I have recalculated the PLR and NLR from their raw data - I disagree with the way they calculated certain things.]

No History of Conjunctivitis

91%

21%

Study: BMJ. 2004 Jul 24;329(7459):206-10. PMID: 15201195. [Note that I have recalculated the PLR and NLR from their raw data - I disagree with the way they calculated certain things.]

Negative Findings

Purulent Secretion

19%

75%

(note that this is not sens / spec at all - in fact it may be slightly less prevalent in bacterial!)

Study: BMJ. 2004 Jul 24;329(7459):206-10. PMID: 15201195. [Note that I have recalculated the PLR and NLR from their raw data - I disagree with the way they calculated certain things.]

Poorly Diagnostic Findings

Bilateral Secretion

37%

84%

Study: BMJ. 2004 Jul 24;329(7459):206-10. PMID: 15201195. [Note that I have recalculated the PLR and NLR from their raw data - I disagree with the way they calculated certain things.]