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Acute Conjunctivitis, Bacterial: Sensitivity and Specificity

Introduction: Acute conjunctivitis can be either viral or bacterial. One study in children had a 54% prevalence of bacterial etiology (42% H flu, 12% S pneumo) and 20% prevalence of adenoviral, with ~30% culture negative [J Pediatr. 1981 Apr;98(4):531-6. PMID: 6970802]. Another study in adults showed that 32% of patients had a bacterial etiology, with 47% S pneumo, 23% S aureus, 16% H flu [BMJ. 2004 Jul 24;329(7459):206-10. PMID: 1520119].

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Tags: Infection Ophthalmology Tag this Diagnosis.

The sensitivity and specificity of findings for Acute Conjunctivitis, Bacterial are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %. Post-Test Probability (Predictive Value): %. Switch to display mode.
**Note that calculating probabilities from more than one finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)
Specific Findings
FindingResult SensitivitySpecificity
[ + ] Bilateral Glued Eyes + 0 - 40%89%
Sensitive Findings
FindingResult SensitivitySpecificity
[ + ] Glued Eyes + 0 - 92%27%
[ + ] No History of Conjunctivitis + 0 - 91%21%
Negative Findings
FindingResult SensitivitySpecificity
[ + ] Purulent Secretion + 0 - 19%75%
Poorly Diagnostic Findings
FindingResult SensitivitySpecificity
[ + ] Bilateral Secretion + 0 - 37%84%