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Elevated Osmolal Gap: Sensitivity and Specificity

Introduction: None written. Excerpt from the entry in Ethylene Glycol Poisoning:
Using equation:

Osmc = 2*Na(mEq/L) + BUN(mmol/L) + glucose(mmol/L) + 1.25*ethanol(mmol/L)

  • OR (in US units) -
  • Osmc (mOsm/kg) = 2(Na+) + [BUN/2.8] + [glucose/18] + 1.25*[ethanol (mg/dL)/4.6]

    Normal is <= 10 mOsm/kg. This is for identifying patients requiring an antidote for overdose.

    [Edit] [Merge finding]

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    Associated Diagnoses:

    Ethylene Glycol Poisoning

    85% sensitive, 50% specific