Tuberculosis: Sensitivity and Specificity
Introduction: Tuberculosis is a major health hazard due to its high contagiousness and ability to exist in a latent state in the host.
Note that the tests have all been assessed for patients with active TB (since there is no gold standard for latent TB).
There are two major tests being used currently to detect latent TB infection - the PPD skin test and the T cell activation blood test.
Note that these are also used in the evaluation of active TB, though they are supplanted (for pulmonary TB) by chest x-ray and sputum AFB stain/culture.