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Good Positive and Negative Likelihood Ratios

Good Positive Likelihood Ratio

Poorly Diagnostic Findings

Thyroid Carcinoma: Likelihood Ratios

Introduction: Note that some of the findings below are listed for nodules and others for actual cancer.

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Tags: Neoplasm Tag this Diagnosis.

Prevalence

Population / CalculatorPrevalence Comments / Study / Link
Thyroid nodules in the general population 67% by ultrasound

Arch Intern Med. 1994 Aug 22;154(16):1838-40. PMID: 8053752

Carcinoma in thyroid nodules 5% note: in this study there was a huge difference in malignancy risk based on nodules discovered incidentally on ultrasound (17%) versus ultrasound studies done for non-incidental reasons (3%)

J Ultrasound Med. 2005 May;24(5):629-34. PMID: 15840794

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The likelihood ratios of findings for Thyroid Carcinoma are listed below. See the left navigation bar to change the display.

Good Positive and Negative Likelihood Ratios

Finding +LR-LR Comments, Study
FNA Edit 9.40.4

for carcinoma as diagnosed by thyroidectomy

note that this sensitivity (and specificity) is an estimate since only 25% of FNA negative patients got thyroidectomy

Study: Ann Surg. 2007 Nov;246(5):714-20. PMID: 17968160

Good Positive Likelihood Ratio

Finding +LR-LR Comments, Study
Palpation Edit inf0.7

for a nodule or nodules, compared to ultrasound

Study: Arch Intern Med. 1994 Aug 22;154(16):1838-40. PMID: 8053752

Poorly Diagnostic Findings

Finding +LR-LR Comments, Study
Solitary Nodule Edit 1.40.7

by ultrasound, for a diagnosis of carcinoma

Study: Surgery. 2007 Dec;142(6):851-7. PMID: 18063067