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Spinal Tumor: Sensitivity and Specificity

Introduction: as a serious cause for back pain (see also Vertebral Fracture in the differential diagnosis)

[Edit Diagnosis] [Merge dx] [Add prevalence]

Tags: Musculoskeletal Neoplasm Tag this Diagnosis.

Prevalence

Population / CalculatorPrevalence Comments / Study / Link
Back Pain 0.1% 0.1-0.7%.
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The sensitivity and specificity of findings for Spinal Tumor are listed below. See the left navigation bar to change the display.

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Finding SensitivitySpecificity Comments, Study
History Edit Sensitivity = 100%

A combination of age >=50 years, a previous history of cancer, unexplained weight loss, and a failure to improve after 1 month of presentation

Study: Best Pract Res Clin Rheumatol. 2008 Jun;22(3):471-82. PMID: 18519100

Red Flags Edit No accuracy specified.

sens not evaluated because no patients had cancer, but false %ve rate (=1-specificity): [selected features below]

  • Age <25/>55 FP 24%
  • Weight loss 0.3%
  • History of CA 4%
  • Systemic sxs 2.3%
  • Clinician dx 0.1%
  • Study: Arthritis Rheum. 2009 Oct;60(10):3072-80. PMID: 19790051