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Spinal Tumor: Sensitivity and Specificity

Introduction: as a serious cause for back pain (see also Vertebral Fracture in the differential diagnosis)

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Tags: Musculoskeletal Neoplasm Tag this Diagnosis.

Prevalence

Population / Calculator	Prevalence	Comments / Study / Link
Back Pain	0.1%	0.1-0.7%.
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The sensitivity and specificity of findings for Spinal Tumor are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %.	Post-Test Probability (Predictive Value): %.	Switch to display mode.
Note that calculating probabilities from more than one** finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)


Finding	Result	Sensitivity	Specificity
[ + ] History		Sensitivity = 100%
A combination of age >=50 years, a previous history of cancer, unexplained weight loss, and a failure to improve after 1 month of presentation Study: Best Pract Res Clin Rheumatol. 2008 Jun;22(3):471-82. PMID: 18519100
[ + ] Red Flags		No accuracy specified.
sens not evaluated because no patients had cancer, but false %ve rate (=1-specificity): [selected features below] Age <25/>55 FP 24% Weight loss 0.3% History of CA 4% Systemic sxs 2.3% Clinician dx 0.1% Study: Arthritis Rheum. 2009 Oct;60(10):3072-80. PMID: 19790051