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Spinal Discitis and Osteomyelitis: Likelihood Ratios

Introduction: Infection of the vertebral bodies, centered at the intervertebral disc. The infection often spreads to the prevertebral soft tissues and into the epidural space. It most commonly affects the lumbar spine.

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Tags: Infection Neurologic Tag this Diagnosis.

The likelihood ratios of findings for Spinal Discitis and Osteomyelitis are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %. Post-Test Probability (Predictive Value): %. Switch to display mode.
**Note that calculating probabilities from more than one finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)
Blood Test
FindingResult +LR-LR
[ + ] Blood Cultures Sensitivity = 56%
[ + ] Elevated CRP Sensitivity = 100%
[ + ] Elevated ESR Sensitivity = 80%
[ + ] Leukocytosis Sensitivity = 40%
Imaging
FindingResult +LR-LR
[ + ] MRI + 0 - 120
Physical Exam
FindingResult +LR-LR
[ + ] Focal Neurological Signs Sensitivity = 40%
Untagged
FindingResult +LR-LR
[ + ] Gallium WBC Scan and Bone Scan + 0 - inf0.1
[ + ] Localized Pain Sensitivity = 95%
[ + ] Spine X-Ray + 0 - 1.90.3
[ + ] Tc99m Bone Scan + 0 - 9.70.1