Septic Arthritis: Sensitivity and Specificity

Introduction: None written.

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Prevalence

Population / Calculator	Prevalence	Comments / Study / Link
Patients presenting with acute monoarthritis	8%	Another study reported 27%. JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
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The sensitivity and specificity of findings for Septic Arthritis are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %.	Post-Test Probability (Predictive Value): %.	Switch to display mode.
Note that calculating probabilities from more than one** finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)


Finding	Result	Sensitivity	Specificity
[ + ] Age	+ 0 -	19%	95%
>80 years Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
[ + ] Diabetes	+ 0 -	12%	96%
Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
[ + ] Elevated CRP	+ 0 -	77%	53%
>100mg/l Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478/JRC70001T2
[ + ] Elevated ESR	+ 0 -	95%	29%
>30mm/hr Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
[ + ] hearing loss	+ 0 -	46%	31%
Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478/JRC70001T2
[ + ] History of HIV	+ 0 -	79%	50%
Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478/JRC70001T2
[ + ] Joint Edema		Sensitivity = 78%
specificity not assessed Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478/JRC70001T2
[ + ] Joint Prosthesis	+ 0 -	35%	89%
for hip or knee Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
[ + ] Leukocytosis	+ 0 -	90%	36%
>10,000/ul Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
[ + ] Pain in Joint		Sensitivity = 85%
specificity not evaluated Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
[ + ] Recent Joint Surgery	+ 0 -	24%	96%
Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
[ + ] Rheumatoid Arthritis	+ 0 -	68%	73%
Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478/JRC70001T2
[ + ] Skin infection	+ 0 -	32%	88%
Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
[ + ] Synovial Glucose	+ 0 -	51%	85%
Low, defined differently in different studies. Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
[ + ] Synovial LDH	+ 0 -	100%	51%
>250 U/L Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
[ + ] Synovial PMN	+ 0 -	73%	79%
>90% Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478/JRC70001T2
[ + ] Synovial Protein	+ 0 -	48%	46%
>3g/dl Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
[ + ] Synovial WBC	+ 0 -	29%	99%
>100k Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
[ + ] Synovial WBC	+ 0 -	62%	92%
>50k Study: JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478