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Septic Arthritis: Sensitivity and Specificity

Introduction: None written.

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Tags: Infection Tag this Diagnosis.

Prevalence

Population / CalculatorPrevalence Comments / Study / Link
Patients presenting with acute monoarthritis 8% Another study reported 27%.

JAMA. 2007;297:1478-1488. http://jama.ama-assn.org/cgi/content/full/297/13/1478
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The sensitivity and specificity of findings for Septic Arthritis are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %. Post-Test Probability (Predictive Value): %. Switch to display mode.
**Note that calculating probabilities from more than one finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)
Specific Findings
FindingResult SensitivitySpecificity
[ + ] Synovial WBC + 0 - 29%99%
[ + ] Recent Joint Surgery + 0 - 24%96%
[ + ] Diabetes + 0 - 12%96%
[ + ] Age + 0 - 19%95%
[ + ] Synovial WBC + 0 - 62%92%
[ + ] Joint Prosthesis + 0 - 35%89%
[ + ] Skin infection + 0 - 32%88%
[ + ] Synovial Glucose + 0 - 51%85%
Sensitive Findings
FindingResult SensitivitySpecificity
[ + ] Synovial LDH + 0 - 100%51%
[ + ] Elevated ESR + 0 - 95%29%
[ + ] Leukocytosis + 0 - 90%36%
[ + ] Pain in Joint Sensitivity = 85%
Negative Findings
FindingResult SensitivitySpecificity
[ + ] Synovial Protein + 0 - 48%46%
[ + ] hearing loss + 0 - 46%31%
Poorly Diagnostic Findings
FindingResult SensitivitySpecificity
[ + ] Synovial PMN + 0 - 73%79%
[ + ] Rheumatoid Arthritis + 0 - 68%73%
[ + ] Elevated CRP + 0 - 77%53%
[ + ] History of HIV + 0 - 79%50%
[ + ] Joint Edema Sensitivity = 78%

 

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