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Rheumatoid Arthritis: Sensitivity and Specificity

Introduction: None written.

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Tags: Autoimmune Musculoskeletal Tag this Diagnosis.

The sensitivity and specificity of findings for Rheumatoid Arthritis are listed below. See the left navigation bar to change the display.

Specific Findings

Finding SensitivitySpecificity Comments, Study
Anti-CCP Antibodies Edit 67%95%

Study: Ann Intern Med. 2007 Jun 5;146(11):797-808. PMID: 17548411

Poorly Diagnostic Findings

Finding SensitivitySpecificity Comments, Study
Rheumatoid Factor Edit 80%80%

specificity 80-95% depending on control population (e.g. age).

Sensitivity may be as low as 60% in initial stages of disease.

Study: Am Fam Physician. 2002 Mar 15;65(6):1073-80. PMID: 11925083

Elevated ESR Edit Sensitivity = 50%

Specificity not listed but reportedly low.

Study: Am Fam Physician. 2002 Mar 15;65(6):1073-80. PMID: 11925083