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Respiratory Syncytial Virus: Sensitivity and Specificity

Introduction: RSV causes bronchiolitis in small children and can also pose a significant threat to immunocompromised and elderly adults.

In children, RSV is the most common etiology of bronchiolitis. In one study, testing of 277 samples revealed 176 (64%) positive for RSV, 44 (16%) for rhinovirus, 26 (9%) for hMPV, 17 (6%) for Flu A, and none for Flu B. [PMID 18275439].

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Tags: Infection Pulmonary Tag this Diagnosis.

Prevalence

Population / CalculatorPrevalence Comments / Study / Link
Bronchiolitis in children 12% Acad Emerg Med. 2008 Feb;15(2):111-8. PMID: 18275439
12%
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The sensitivity and specificity of findings for Respiratory Syncytial Virus are listed below. See the left navigation bar to change the display.

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Finding SensitivitySpecificity Comments, Study
DFA Swab Edit 93%92%

Study: Pediatr Infect Dis J. 2007 Nov;26(11 Suppl):S36-40. PMID: 18090198

Swab DIA Edit 93%91%

Study: Pediatr Infect Dis J. 2007 Nov;26(11 Suppl):S36-40. PMID: 18090198

Swab EIA Edit 59%75%

Study: Pediatr Infect Dis J. 2007 Nov;26(11 Suppl):S36-40. PMID: 18090198

Swab OIA Edit 88%97%

Study: Pediatr Infect Dis J. 2007 Nov;26(11 Suppl):S36-40. PMID: 18090198

Swab RT-PCR Edit 100%100%

"nearly 100%" sensitivity and specificity

Study: Pediatr Infect Dis J. 2007 Nov;26(11 Suppl):S36-40. PMID: 18090198