Respiratory Syncytial Virus: Likelihood Ratios

Introduction: RSV causes bronchiolitis in small children and can also pose a significant threat to immunocompromised and elderly adults.

In children, RSV is the most common etiology of bronchiolitis. In one study, testing of 277 samples revealed 176 (64%) positive for RSV, 44 (16%) for rhinovirus, 26 (9%) for hMPV, 17 (6%) for Flu A, and none for Flu B. [PMID 18275439].

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Prevalence

The likelihood ratios of findings for Respiratory Syncytial Virus are listed below. See the left navigation bar to change the display.

Good Positive and Negative Likelihood Ratios

Finding	+LR	-LR	Comments, Study
Swab RT-PCR	inf	0	"nearly 100%" sensitivity and specificity Study: Pediatr Infect Dis J. 2007 Nov;26(11 Suppl):S36-40. PMID: 18090198
Swab OIA	29.3	0.1	Study: Pediatr Infect Dis J. 2007 Nov;26(11 Suppl):S36-40. PMID: 18090198
DFA Swab	11.6	0.1	Study: Pediatr Infect Dis J. 2007 Nov;26(11 Suppl):S36-40. PMID: 18090198
Swab DIA	10.3	0.1	Study: Pediatr Infect Dis J. 2007 Nov;26(11 Suppl):S36-40. PMID: 18090198
Swab EIA	2.4	0.5	Study: Pediatr Infect Dis J. 2007 Nov;26(11 Suppl):S36-40. PMID: 18090198