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Preterm Labor: Sensitivity and Specificity

Introduction: Generally defined as birth <37 weeks. See also tests to determine Risk of Preterm Labor. The patients here are symptomatic with labor.

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Tags: Obstetrical Tag this Diagnosis.

Prevalence

Population / CalculatorPrevalence Comments / Study / Link
women hospitalized for preterm labor between 18 and 34 completed weeks' gestation 13.4% for delivery <35wk

Am J Obstet Gynecol. 2006 Jan;194(1):138-43. PMID 16389023

Women with preterm labor 17.1% for delivery within 28 days

Acta Obstet Gynecol Scand. 2002 Jan;81(1):58-63. PMID 11942889

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The sensitivity and specificity of findings for Preterm Labor are listed below. See the left navigation bar to change the display.

Sensitive and Specific Findings

Finding SensitivitySpecificity Comments, Study
Cervical Length Plus fFN
Duplicate Edit
86%90%

cervical length <=20mm OR length 21-31mm + positive fFN

for delivery within 28 days

Study: Acta Obstet Gynecol Scand. 2002 Jan;81(1):58-63. PMID 11942889

Poorly Diagnostic Findings

Finding SensitivitySpecificity Comments, Study
Cervical Length Plus fFN
Duplicate Edit
67%81%

cervical length <=15mm OR cervical length 16-30mm + fFN >=50ng/ml

for delivery <35wk

in this study, results not significantly different from using fetal fibronectin alone (but saves fFN tests)

Study: Am J Obstet Gynecol. 2006 Jan;194(1):138-43. PMID 16389023

Fetal Fibronectin Edit 63%81%

>=50ng/ml, for delivery <35 wk

Study: Am J Obstet Gynecol. 2006 Jan;194(1):138-43. PMID 16389023

Cervical Length Edit 75%63%

cervical length <=25mm

for delivery <35 wk

Study: Am J Obstet Gynecol. 2006 Jan;194(1):138-43. PMID 16389023