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Combination of Tests

Peripheral Arterial Disease: Sensitivity and Specificity

Introduction: None written.

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Tags: Vascular Tag this Diagnosis.

Prevalence

Population / Calculator	Prevalence	Comments / Study / Link
Symptomatic adults age 60-80	15%	JAMA. 2006 Feb 1;295(5):536-46. PMID: 16449619
Asymptomatic Adults, age 60-69	5%	JAMA. 2006 Feb 1;295(5):536-46. PMID: 16449619
More populations	0%	see table 5 in JAMA. 2006 Feb 1;295(5):536-46. PMID: 16449619
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The sensitivity and specificity of findings for Peripheral Arterial Disease are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %.	Post-Test Probability (Predictive Value): %.	Switch to display mode.
Note that calculating probabilities from more than one** finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)

Combination of Tests
Finding	Result	Sensitivity	Specificity
[ + ] Peripheral Artery Disease Score	+ 0 -	82%	89%
< 6 of the following in asymptomatic patients: The number of auscultated components (right posterior tibial artery + left posterior tibial artery; range of 0 for none heard to 3 for normal for each artery) plus The grade of palpated posterior tibial artery (right posterior tibial artery + left posterior tibial artery; 2 for normal, 1 for palpated but abnormal, 0 for not palpable for each artery) plus A history of myocardial infarction (1 for none, 0 for prior myocardial infarction) Study: JAMA. 2006 Feb 1;295(5):536-46. PMID: 16449619

History
Finding	Result	Sensitivity	Specificity
[ + ] Intermittent Claudication	+ 0 -	15%	95%
reproducible leg pain that occurs with exercise, does not occur at rest, and is relieved within 10 minutes of rest (in a screening population) Study: JAMA. 2006 Feb 1;295(5):536-46. PMID: 16449619

Imaging
Finding	Result	Sensitivity	Specificity
[ + ] CT angiography	+ 0 -	95%	96%
most of data from patients with intermittent claudication Study: JAMA. 2009;301(4):415-424. http://jama.ama-assn.org/cgi/content/short/301/4/415

lr
Finding	Result	Sensitivity	Specificity
[ + ] Intermittent Claudication	+ 0 -	15%	95%
reproducible leg pain that occurs with exercise, does not occur at rest, and is relieved within 10 minutes of rest (in a screening population) Study: JAMA. 2006 Feb 1;295(5):536-46. PMID: 16449619

Untagged
Finding	Result	Sensitivity	Specificity
[ + ] Ankle-Brachial Index	+ 0 -	95%	100%
Threshold < 0.9 With the patient lying supine, a sphygmomanometer cuff, placed 2 to 3 cm above the point of pulse measurement, is inflated above the systolic pressure. As the cuff pressure is slowly released, a handheld Doppler is used for obtaining the systolic pressure at the right and left ankle (either dorsalis pedis artery, posterior tibial artery, or both) and the right and left brachial artery. The systolic pressure is that pressure where the Doppler signal returns. Study: JAMA. 2006 Feb 1;295(5):536-46. PMID: 16449619