Neurofibromatosis Type 2 (NF2): Sensitivity and Specificity

Introduction: None written.

Prevalence

Overall

0.00004%

1 in 25,000 individuals are thought to have NF2

Eur J Med Res. 2009 Mar 17;14(3):102-5.

Neurofibromatosis.

Gerber PA, Antal AS, Neumann NJ, Homey B, Matuschek C, Peiper M, Budach W, Bölke E.

Department of Dermatology, Heinrich-Heine-Universität Düsseldorf, Germany.

The sensitivity and specificity of findings for Neurofibromatosis Type 2 (NF2) are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %.	Post-Test Probability (Predictive Value): %.	Switch to display mode.
Note that calculating probabilities from more than one** finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)

Findings With Unspecified Accuracy
Finding	Result	Sensitivity	Specificity
[ + ] Acoustic Neuroma, unilateral		No accuracy specified.
Study: no study specified.
[ + ] Acoustic Neuroma, Bilateral		No accuracy specified.
The finding of bilateral acoustic neuromas is pathogneumonic for NF2. Therefore the specificity should be 100% Study: no study specified.