Neuroblastoma: Sensitivity and Specificity

Introduction: None written.

The sensitivity and specificity of findings for Neuroblastoma are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %.	Post-Test Probability (Predictive Value): %.	Switch to display mode.
Note that calculating probabilities from more than one** finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)


Finding	Result	Sensitivity	Specificity
[ + ] Dopamine / Cr Ratio	+ 0 -	65%	82%
from urine Study: Ann Clin Biochem. 2006 Jul;43(Pt 4):300-5. PMID: 16824281
[ + ] Urine Dopamine		Sensitivity = 61.3%
specificity not assessed Study: Ann Clin Biochem. 2006 Jul;43(Pt 4):300-5. PMID: 16824281
[ + ] Urine Elevated VMA, HA, or DA		Sensitivity = 91.2%
specificity not assessed Study: Ann Clin Biochem. 2006 Jul;43(Pt 4):300-5. PMID: 16824281
[ + ] Urine Homovanillic Acid		Sensitivity = 71.9%
specificity not assessed Study: Ann Clin Biochem. 2006 Jul;43(Pt 4):300-5. PMID: 16824281
[ + ] Urine Vanillylmandelic Acid		Sensitivity = 80.7%
specificity not assessed Study: Ann Clin Biochem. 2006 Jul;43(Pt 4):300-5. PMID: 16824281
[ + ] VMA / Cr Ratio	+ 0 -	95%	85.9%
from urine. Ratio was compared to a floating median. Study: Ann Clin Biochem. 2006 Jul;43(Pt 4):300-5. PMID: 16824281