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Necrotizing Fasciitis: Sensitivity and Specificity

Introduction: An extremely deadly soft tissue infection involving the deep fascia. This may be caused by Group A Streptococcus or gas-forming organisms such as Clostridium perfringens.

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Tags: Infection Musculoskeletal Tag this Diagnosis.

The sensitivity and specificity of findings for Necrotizing Fasciitis are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %. Post-Test Probability (Predictive Value): %. Switch to display mode.
**Note that calculating probabilities from more than one finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)
Sensitive and Specific Findings
FindingResult SensitivitySpecificity
[ + ] MRI + 0 - 100%86%
Sensitive Findings
FindingResult SensitivitySpecificity
[ + ] CT Scan + 0 - 100%81%
[ + ] Leukocytosis or Hyponatremia + 0 - 90%76%
Poorly Diagnostic Findings
FindingResult SensitivitySpecificity
[ + ] Laboratory Risk Indicator in Necrotising Fasciitis + 0 - 80%67%