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Mycoplasma Pneumonia: Likelihood Ratios

Introduction: Mycoplasma is one of the causes of an atypical Community Acquired Pneumonia.

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Tags: Infection Pulmonary Tag this Diagnosis.

Prevalence

Population / CalculatorPrevalence Comments / Study / Link
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The likelihood ratios of findings for Mycoplasma Pneumonia are listed below. See the left navigation bar to change the display.

Good Positive Likelihood Ratio

Finding +LR-LR Comments, Study
Mycoplasma PCR Edit inf0.6

sensitivity ~20% in young adults and 9% in children

sensitivity 50% in first 3 weeks of infection

Study: Clin Infect Dis. 2009 May 1;48(9):1244-9. PMID 19331586

Mycoplasma IgM Edit 2.20.7

much more sensitive (90-100%) but less specific in young adults / children

sensitivity 76% in first 3 weeks rising to 100% by 2 months in all comers

Study: Clin Infect Dis. 2009 May 1;48(9):1244-9. PMID 19331586

Poorly Diagnostic Findings

Finding +LR-LR Comments, Study
Mycoplasma IgG + IgM Edit 1.90.8

sensitivity higher and specificity lower in young adults / children

sensitivity 33% in first 3 weeks up to 76% at 2 months in all comers

Study: Clin Infect Dis. 2009 May 1;48(9):1244-9. PMID 19331586

Cold Agglutinins Edit Sensitivity = 50%

IgM antibodies; develop 1-2 weeks after infection

Study: Clin Infect Dis 1993 Aug;17 Suppl 1:S79-82. PMID 8399943