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Mycoplasma Pneumonia: Sensitivity and Specificity

Introduction: Mycoplasma is one of the causes of an atypical Community Acquired Pneumonia.

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Tags: Infection Pulmonary Tag this Diagnosis.

Prevalence

Population / Calculator	Prevalence	Comments / Study / Link
10000	0%
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The sensitivity and specificity of findings for Mycoplasma Pneumonia are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %.	Post-Test Probability (Predictive Value): %.	Switch to display mode.
Note that calculating probabilities from more than one** finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)

Untagged
Finding	Result	Sensitivity	Specificity
[ + ] Cold Agglutinins		Sensitivity = 50%
IgM antibodies; develop 1-2 weeks after infection Study: Clin Infect Dis 1993 Aug;17 Suppl 1:S79-82. PMID 8399943
[ + ] Mycoplasma IgG + IgM	+ 0 -	35%	82%
sensitivity higher and specificity lower in young adults / children sensitivity 33% in first 3 weeks up to 76% at 2 months in all comers Study: Clin Infect Dis. 2009 May 1;48(9):1244-9. PMID 19331586
[ + ] Mycoplasma IgM	+ 0 -	40%	82%
much more sensitive (90-100%) but less specific in young adults / children sensitivity 76% in first 3 weeks rising to 100% by 2 months in all comers Study: Clin Infect Dis. 2009 May 1;48(9):1244-9. PMID 19331586
[ + ] Mycoplasma PCR	+ 0 -	40%	100%
sensitivity ~20% in young adults and 9% in children sensitivity 50% in first 3 weeks of infection Study: Clin Infect Dis. 2009 May 1;48(9):1244-9. PMID 19331586