Microalbuminuria: Sensitivity and Specificity

Introduction: Defined by >=30mg of albumin in a 24-hour urine sample. This is often a precursor to nephrotic-range kidney damage by hypertension or diabetes mellitus.

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Prevalence

Population / Calculator	Prevalence	Comments / Study / Link
General population	6.1%	patients from PREVEND trial, "reweighted" by computer-based random sampling Kidney Int Suppl. 2005 Apr;(94):S28-35 PMID 15752236
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The sensitivity and specificity of findings for Microalbuminuria are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %.	Post-Test Probability (Predictive Value): %.	Switch to display mode.
Note that calculating probabilities from more than one** finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)

Sensitive and Specific Findings
Finding	Result	Sensitivity	Specificity
[ + ] Urine Albumin to Creatinine Ratio	+ 0 -	87.6%	87.5%
>9.9mg/g Study: Kidney Int Suppl. 2005 Apr;(94):S28-35 PMID 15752236
[ + ] Spot Urine Albumin	+ 0 -	85%	85%
>11.2mg/L in a screening population Study: Kidney Int Suppl. 2005 Apr;(94):S28-35 PMID 15752236