Menopause: Sensitivity and Specificity

Introduction: Two good articles:

and J Fam Pract. 2005 Nov;54(11):1000-2. PMID: 16266610

The sensitivity and specificity of findings for Menopause are listed below. See the left navigation bar to change the display.

Specific Findings

Finding	Sensitivity	Specificity	Comments, Study
Amenorrhea	20%	99%	3-12 month duration Study: J Fam Pract. 2005 Nov;54(11):1000-2. PMID: 16266610
Age	35%	98%	>= 50 years Study: J Fam Pract. 2005 Nov;54(11):1000-2. PMID: 16266610
Inhibin Duplicate	7%	96%	inhibin immunoreactivity Study: J Fam Pract. 2005 Nov;54(11):1000-2. PMID: 16266610
Vaginal Dryness	20%	88%	Study: J Fam Pract. 2005 Nov;54(11):1000-2. PMID: 16266610
Hot Flashes	40%	87%	Study: J Fam Pract. 2005 Nov;54(11):1000-2. PMID: 16266610
Elevated FSH	69%	86%	>20 or >24 IU/l, depending on study Study: J Fam Pract. 2005 Nov;54(11):1000-2. PMID: 16266610

Sensitive Findings

85%

51%

Study: J Fam Pract. 2005 Nov;54(11):1000-2. PMID: 16266610

Poorly Diagnostic Findings

Finding	Sensitivity	Specificity	Comments, Study
Menstrual Irregularity	66%	81%	within last 12 months Study: J Fam Pract. 2005 Nov;54(11):1000-2. PMID: 16266610
Night Sweats	35%	80%	Study: J Fam Pract. 2005 Nov;54(11):1000-2. PMID: 16266610
Inhibin Duplicate	46%	78%	inhibin B Study: J Fam Pract. 2005 Nov;54(11):1000-2. PMID: 16266610
Inhibin Duplicate	61%	54%	inhibin A Study: J Fam Pract. 2005 Nov;54(11):1000-2. PMID: 16266610
Change in Menstrual Flow	81%	30%	Study: J Fam Pract. 2005 Nov;54(11):1000-2. PMID: 16266610