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Menopause: Likelihood Ratios

Introduction: Two good articles:

Bastian, et al. JAMA 2003 http://jama.ama-assn.org/cgi/content/full/289/7/895

and J Fam Pract. 2005 Nov;54(11):1000-2. PMID: 16266610

[Edit Diagnosis] [Merge dx] [Add prevalence]

Tags: Endocrine Gynecologic Tag this Diagnosis.

The likelihood ratios of findings for Menopause are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %. Post-Test Probability (Predictive Value): %. Switch to display mode.
**Note that calculating probabilities from more than one finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)
Good Positive and Negative Likelihood Ratios
FindingResult +LR-LR
[ + ] Elevated FSH + 0 - 4.90.4
[ + ] Menstrual Irregularity + 0 - 3.50.4
Good Negative Likelihood Ratio
FindingResult +LR-LR
[ + ] Patient Thinks She is Perimenopausal + 0 - 1.70.3
Good Positive Likelihood Ratio
FindingResult +LR-LR
[ + ] Amenorrhea + 0 - 200.8
[ + ] Age + 0 - 17.50.7
[ + ] Hot Flashes + 0 - 3.10.7
[ + ] Inhibin + 0 - 2.10.7
Poorly Diagnostic Findings
FindingResult +LR-LR
[ + ] Inhibin + 0 - 1.81
[ + ] Vaginal Dryness + 0 - 1.70.9
[ + ] Night Sweats + 0 - 1.80.8
[ + ] Inhibin + 0 - 1.30.7
[ + ] Change in Menstrual Flow + 0 - 1.20.6