Irritable Bowel Syndrome: Sensitivity and Specificity

Introduction: None written.

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Prevalence

Population / Calculator	Prevalence	Comments / Study / Link
General population	5%	by Rome I criteria Aliment Pharmacol Ther. 2004 Aug 1;20(3):339-45. PMID 15274671
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The sensitivity and specificity of findings for Irritable Bowel Syndrome are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %.	Post-Test Probability (Predictive Value): %.	Switch to display mode.
Note that calculating probabilities from more than one** finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)


Finding	Result	Sensitivity	Specificity
[ + ] Feeling of incomplete evacuation	+ 0 -	74%	45%
Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793
[ + ] Kruis Scoring System	+ 0 -	77%	89%
>=44 points Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793
[ + ] Looser stools at onset of pain	+ 0 -	58%	73%
Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793
[ + ] Lower abdominal pain	+ 0 -	90%	32%
Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793
[ + ] Manning Criteria	+ 0 -	78%	72%
>=3: Abdominal pain relieved by defecation More frequent stools at onset of pain Looser stools with onset of pain Passage of mucus per rectum Feeling of incomplete evacuation Patient-reported visible abdominal distension Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793
[ + ] More frequent stools at onset of pain	+ 0 -	53%	72%
Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793
[ + ] Mucus per rectum	+ 0 -	45%	62%
Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793
[ + ] Pain relieved by defecation	+ 0 -	60%	66%
Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793
[ + ] Patient-reported abdominal distension	+ 0 -	39%	77%
Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793
[ + ] Rome I Criteria	+ 0 -	71%	85%
Abdominal pain or discomfort relieved with defecation or associated with a change in stool frequency or consistency (>= 3 months), plus >= 2 of the following on at least 25% of occasions: Altered stool frequency Altered stool form Altered stool passage Passage of mucus per rectum Bloating or distension Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793