Irritable Bowel Syndrome: Sensitivity and Specificity

Introduction: None written.

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Prevalence

Population / Calculator	Prevalence	Comments / Study / Link
General population	5%	by Rome I criteria Aliment Pharmacol Ther. 2004 Aug 1;20(3):339-45. PMID 15274671
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The sensitivity and specificity of findings for Irritable Bowel Syndrome are listed below. See the left navigation bar to change the display.

Specific Findings

Kruis Scoring System

77%

89%

>=44 points

Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793

Rome I Criteria

71%

85%

Abdominal pain or discomfort relieved with defecation or associated with a change in stool frequency or consistency (>= 3 months), plus >= 2 of the following on at least 25% of occasions:

Altered stool frequency

Altered stool form

Altered stool passage

Passage of mucus per rectum

Bloating or distension

Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793

Sensitive Findings

Lower abdominal pain

90%

32%

Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793

Poorly Diagnostic Findings

Finding	Sensitivity	Specificity	Comments, Study
Patient-reported abdominal distension	39%	77%	Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793
Looser stools at onset of pain	58%	73%	Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793
Manning Criteria	78%	72%	>=3: Abdominal pain relieved by defecation More frequent stools at onset of pain Looser stools with onset of pain Passage of mucus per rectum Feeling of incomplete evacuation Patient-reported visible abdominal distension Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793
More frequent stools at onset of pain	53%	72%	Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793
Pain relieved by defecation	60%	66%	Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793
Mucus per rectum	45%	62%	Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793
Feeling of incomplete evacuation	74%	45%	Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793