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Interstitial Lung Disease: Sensitivity and Specificity

Introduction: The below accuracies will be for non-Idiopathic Pulmonary Fibrosis types of ILD.

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The sensitivity and specificity of findings for Interstitial Lung Disease are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %.	Post-Test Probability (Predictive Value): %.	Switch to display mode.
Note that calculating probabilities from more than one** finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)

Sensitive Findings
Finding	Result	Sensitivity	Specificity
[ + ] Clinical diagnosis	+ 0 -	88.8%	40%
Clinical diagnosis includes: history, HRCT, and bronchoscopy (gold standard is lung biopsy). Community patients referred for further definitive diagnostic evaluation of new-onset, untreated nonspecific ILD. Study: Chest. 1999 Nov;116(5):1168-74. PMID: 10559072

Negative Findings
Finding	Result	Sensitivity	Specificity
[ + ] High-Resolution Chest CT (HRCT)	+ 0 -	59%	40%
Community patients referred for further definitive diagnostic evaluation of new-onset, untreated nonspecific ILD. Study: Chest. 1999 Nov;116(5):1168-74. PMID: 10559072