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Poorly Diagnostic Findings

Insulin Resistance: Sensitivity and Specificity

Introduction: As opposed to overt Diabetes. Insulin resistance is a component of the metabolic syndrome, along with hypertension, obesity, and dyslipidemia.

Gold standard is euglycemic hyperinsulinemic clamp, where a constant insulin infusion is given and a separate glucose infusion is titrated to euglycemia. The lower the amount of glucose needed, the more insulin resistant a person is.

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Tags: Endocrine Tag this Diagnosis.

The sensitivity and specificity of findings for Insulin Resistance are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %. Post-Test Probability (Predictive Value): %. Switch to display mode.
**Note that calculating probabilities from more than one finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)
Specific Findings
FindingResult SensitivitySpecificity
[ + ] Fasting Insulin + 0 - 57%85%
[ + ] ATP III Criteria + 0 - 52%85%
Poorly Diagnostic Findings
FindingResult SensitivitySpecificity
[ + ] Acanthosis Nigricans + 0 - 50%83%
[ + ] Body Mass Index + 0 - 56%76%
[ + ] Elevated Triglycerides + 0 - 67%71%
[ + ] Triglyceride to HDL Ratio + 0 - 64%68%