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Good Positive and Negative Likelihood Ratios

Good Positive Likelihood Ratio

Poorly Diagnostic Findings

Infectious Mononucleosis: Likelihood Ratios

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The likelihood ratios of findings for Infectious Mononucleosis are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %.	Post-Test Probability (Predictive Value): %.	Switch to display mode.
Note that calculating probabilities from more than one** finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)

Good Positive and Negative Likelihood Ratios
Finding	Result	+LR	-LR
[ + ] Lymphocytosis	+ 0 -	14	0.2
Study: Ebell, M. H., Call, M., Shinholser, J., & Gardner, J. (2016). Does This Patient Have Infectious Mononucleosis? JAMA, 315(14), 1502. doi:10.1001/jama.2016.2111

Good Positive Likelihood Ratio
Finding	Result	+LR	-LR
[ + ] Leukocytosis	+ 0 -	3.1	0.7
Study: Ebell, M. H., Call, M., Shinholser, J., & Gardner, J. (2016). Does This Patient Have Infectious Mononucleosis? JAMA, 315(14), 1502. doi:10.1001/jama.2016.2111
[ + ] Tonsillar Exudate	+ 0 -	2.1	0.8
Study: Ebell, M. H., Call, M., Shinholser, J., & Gardner, J. (2016). Does This Patient Have Infectious Mononucleosis? JAMA, 315(14), 1502. doi:10.1001/jama.2016.2111

Poorly Diagnostic Findings
Finding	Result	+LR	-LR
[ + ] Pharyngeal Exudate	+ 0 -	1.9	0.9
Study: Ebell, M. H., Call, M., Shinholser, J., & Gardner, J. (2016). Does This Patient Have Infectious Mononucleosis? JAMA, 315(14), 1502. doi:10.1001/jama.2016.2111
[ + ] Rash	+ 0 -	0.8	1
Study: Ebell, M. H., Call, M., Shinholser, J., & Gardner, J. (2016). Does This Patient Have Infectious Mononucleosis? JAMA, 315(14), 1502. doi:10.1001/jama.2016.2111
[ + ] Sore throat		Sensitivity = 81%
Study: Ebell, M. H., Call, M., Shinholser, J., & Gardner, J. (2016). Does This Patient Have Infectious Mononucleosis? JAMA, 315(14), 1502. doi:10.1001/jama.2016.2111
[ + ] Fever		Sensitivity = 72%
Study: Ebell, M. H., Call, M., Shinholser, J., & Gardner, J. (2016). Does This Patient Have Infectious Mononucleosis? JAMA, 315(14), 1502. doi:10.1001/jama.2016.2111
[ + ] Headache		Sensitivity = 66%
Study: Ebell, M. H., Call, M., Shinholser, J., & Gardner, J. (2016). Does This Patient Have Infectious Mononucleosis? JAMA, 315(14), 1502. doi:10.1001/jama.2016.2111
[ + ] Splenomegaly		Sensitivity = 26%
Study: Ebell, M. H., Call, M., Shinholser, J., & Gardner, J. (2016). Does This Patient Have Infectious Mononucleosis? JAMA, 315(14), 1502. doi:10.1001/jama.2016.2111
[ + ] Hepatomegaly		Sensitivity = 15%
Study: Ebell, M. H., Call, M., Shinholser, J., & Gardner, J. (2016). Does This Patient Have Infectious Mononucleosis? JAMA, 315(14), 1502. doi:10.1001/jama.2016.2111