Infectious Mononucleosis: Sensitivity and Specificity

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The sensitivity and specificity of findings for Infectious Mononucleosis are listed below. See the left navigation bar to change the display.

Specific Findings

Finding	Sensitivity	Specificity	Comments, Study
Lymphocytosis	84%	94%	Study: Ebell, M. H., Call, M., Shinholser, J., & Gardner, J. (2016). Does This Patient Have Infectious Mononucleosis? JAMA, 315(14), 1502. doi:10.1001/jama.2016.2111
Pharyngeal Exudate	13%	93%	Study: Ebell, M. H., Call, M., Shinholser, J., & Gardner, J. (2016). Does This Patient Have Infectious Mononucleosis? JAMA, 315(14), 1502. doi:10.1001/jama.2016.2111
Leukocytosis	40%	87%	Study: Ebell, M. H., Call, M., Shinholser, J., & Gardner, J. (2016). Does This Patient Have Infectious Mononucleosis? JAMA, 315(14), 1502. doi:10.1001/jama.2016.2111
Rash	11%	86%	Study: Ebell, M. H., Call, M., Shinholser, J., & Gardner, J. (2016). Does This Patient Have Infectious Mononucleosis? JAMA, 315(14), 1502. doi:10.1001/jama.2016.2111

Negative Findings

Rash

11%

86%

Study: Ebell, M. H., Call, M., Shinholser, J., & Gardner, J. (2016). Does This Patient Have Infectious Mononucleosis? JAMA, 315(14), 1502. doi:10.1001/jama.2016.2111

Poorly Diagnostic Findings

Finding	Sensitivity	Specificity	Comments, Study
Tonsillar Exudate	33%	84%	Study: Ebell, M. H., Call, M., Shinholser, J., & Gardner, J. (2016). Does This Patient Have Infectious Mononucleosis? JAMA, 315(14), 1502. doi:10.1001/jama.2016.2111
Sore throat	Sensitivity = 81%		Study: Ebell, M. H., Call, M., Shinholser, J., & Gardner, J. (2016). Does This Patient Have Infectious Mononucleosis? JAMA, 315(14), 1502. doi:10.1001/jama.2016.2111
Fever	Sensitivity = 72%		Study: Ebell, M. H., Call, M., Shinholser, J., & Gardner, J. (2016). Does This Patient Have Infectious Mononucleosis? JAMA, 315(14), 1502. doi:10.1001/jama.2016.2111
Headache	Sensitivity = 66%		Study: Ebell, M. H., Call, M., Shinholser, J., & Gardner, J. (2016). Does This Patient Have Infectious Mononucleosis? JAMA, 315(14), 1502. doi:10.1001/jama.2016.2111
Splenomegaly	Sensitivity = 26%		Study: Ebell, M. H., Call, M., Shinholser, J., & Gardner, J. (2016). Does This Patient Have Infectious Mononucleosis? JAMA, 315(14), 1502. doi:10.1001/jama.2016.2111
Hepatomegaly	Sensitivity = 15%		Study: Ebell, M. H., Call, M., Shinholser, J., & Gardner, J. (2016). Does This Patient Have Infectious Mononucleosis? JAMA, 315(14), 1502. doi:10.1001/jama.2016.2111