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Good Positive and Negative Likelihood Ratios

Good Positive Likelihood Ratio

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Hypothyroidism: Likelihood Ratios

Introduction: None written.

[Edit Diagnosis] [Merge dx] [Add prevalence]

Tags: Endocrine Tag this Diagnosis.

The likelihood ratios of findings for Hypothyroidism are listed below. See the left navigation bar to change the display.

Good Positive and Negative Likelihood Ratios

Finding +LR-LR Comments, Study
TSH
Duplicate Edit		 13.10.1

exact sens / spec depends on the particular TSH assay used

Study: Arch Intern Med 1989 Mar;149(3):526-32. PMID 2493228
Free T4
Duplicate Edit		 13.70.2

estimated

Study: Arch Intern Med 1989 Mar;149(3):526-32. PMID 2493228
Achilles Reflex Edit 12.80.2

delayed relaxation time

Study: J Clin Endocrinol Metab. 1997 Mar;82(3):771-6. PMID: 9062480
Free T4
Duplicate Edit		 11.10.2

calculated

Study: Arch Intern Med 1989 Mar;149(3):526-32. PMID 2493228
Free T3 Edit 7.20.2

Study: Arch Intern Med 1989 Mar;149(3):526-32. PMID 2493228
Periorbital Puffiness Edit 150.4

obscuring the curve of the malar bone.

Note that another study [PMID: 15047991] gave sens = 92% / spec = 21%.

Study: J Clin Endocrinol Metab. 1997 Mar;82(3):771-6. PMID: 9062480
Dry Skin Edit 2.10.4

Study: J Clin Endocrinol Metab. 1997 Mar;82(3):771-6. PMID: 9062480
Decreased Sweating Edit 3.90.5

Study: J Clin Endocrinol Metab. 1997 Mar;82(3):771-6. PMID: 9062480
Coarse Skin Edit 3.20.5

Study: J Clin Endocrinol Metab. 1997 Mar;82(3):771-6. PMID: 9062480

Good Positive Likelihood Ratio

Finding +LR-LR Comments, Study
Slow Movements Edit 360.6

Note that another study [PMID: 15047991] gave sens = 87%, spec = 13%.

Study: J Clin Endocrinol Metab. 1997 Mar;82(3):771-6. PMID: 9062480
Hearing Loss Edit 110.8

progressive

Study: J Clin Endocrinol Metab. 1997 Mar;82(3):771-6. PMID: 9062480
Constipation Edit 3.20.6

Study: J Clin Endocrinol Metab. 1997 Mar;82(3):771-6. PMID: 9062480
Paresthesias Edit 3.10.6

Study: J Clin Endocrinol Metab. 1997 Mar;82(3):771-6. PMID: 9062480
Hoarseness Edit 2.80.8

Study: J Clin Endocrinol Metab. 1997 Mar;82(3):771-6. PMID: 9062480
Cold Skin Edit 2.50.6

Study: J Clin Endocrinol Metab. 1997 Mar;82(3):771-6. PMID: 9062480
Weight Gain Edit 2.30.6

or tightness of clothes

Study: J Clin Endocrinol Metab. 1997 Mar;82(3):771-6. PMID: 9062480

Poorly Diagnostic Findings

Finding +LR-LR Comments, Study
Cold Intolerance Edit 1.80.6

Study: J Clin Endocrinol Metab. 1997 Mar;82(3):771-6. PMID: 9062480
Bradycardia Edit 11

Study: J Clin Endocrinol Metab. 1997 Mar;82(3):771-6. PMID: 9062480
Peripheral Edema Edit 1.10.7

specifically pre-tibial

Study: J Postgrad Med. 2004 Jan-Mar;50(1):7-11. PMID: 15047991

Findings With Unspecified Accuracy

Finding +LR-LR Comments, Study
TSH
Duplicate Edit		 No accuracy specified.

Study: no study specified.

 

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