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Hyperaldosteronism: Likelihood Ratios

Introduction: Also known as Conn's syndrome, this is an endocrine cause of hypertension, resulting either from an adrenal adenoma or bilateral adrenal hyperplasia. The high aldosterone levels cause retention of sodium and loss of potassium and hydrogen ions. There is also secondary suppression of renin levels.

Blood tests must be done off of any drugs that could interfere with the renin-angiotensin-aldosterone axis.

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Tags: Endocrine Tag this Diagnosis.

The likelihood ratios of findings for Hyperaldosteronism are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %. Post-Test Probability (Predictive Value): %. Switch to display mode.
**Note that calculating probabilities from more than one finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)
Good Positive and Negative Likelihood Ratios
FindingResult +LR-LR
[ + ] Aldosterone to Renin Ratio + 0 - inf0
[ + ] Aldosterone to Renin Ratio + 0 - inf0
[ + ] Aldosterone to Renin Ratio + 0 - 8.70
[ + ] Plasma Aldosterone + 0 - 4.30
[ + ] Plasma Renin Activity + 0 - 8.20.1
[ + ] Plasma Aldosterone + 0 - 4.20.1
Findings With Unspecified Accuracy
FindingResult +LR-LR
[ + ] Hypokalemia No accuracy specified.