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Hirschsprung's Disease: Likelihood Ratios

Introduction: Hirschsprung's disease, technically congenital aganglionic megacolon, results from incomplete migration of the neural crest precursor cells that are the progenitors of the ganglion cells that innervate the large intestine. Thus, this disease is manifested by lack of intestinal motility distal to a certain point.

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Tags: Congenital Gastrointestinal Problem Tag this Diagnosis.

The likelihood ratios of findings for Hirschsprung's Disease are listed below. See the left navigation bar to change the display.

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Finding +LR-LR Comments, Study
Anorectal Manometry Edit 11.90.2

Study: J Pediatr. 2005 Jun;146(6):787-92 PMID: 15973319

Contrast enema Edit 25.30.2

Study: J Pediatr. 2005 Jun;146(6):787-92 PMID: 15973319

Rectal suction biopsy Edit inf0.1

Study: J Pediatr. 2005 Jun;146(6):787-92 PMID: 15973319