Gout: Sensitivity and Specificity

Introduction: None written.

The sensitivity and specificity of findings for Gout are listed below. See the left navigation bar to change the display.

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Finding	Sensitivity	Specificity	Comments, Study
Monosodium Urate Crystals Duplicate	84%	100%	in synovial fluid during an acute attack Study: Ann Rheum Dis. 2006 Oct;65(10):1301-11. PMID: 16707533
Monosodium Urate Crystals Duplicate	70%	95%	from synovial fluid in asymptomatic patients, i.e. in between attacks Study: Ann Rheum Dis. 2006 Oct;65(10):1301-11. PMID: 16707533
Podagra	96%	97%	i.e. clinical acute involvement of the great toe Study: Ann Rheum Dis. 2006 Oct;65(10):1301-11. PMID: 16707533
Tophus on pinna	No accuracy specified.		Tophus may exude a chalky white substance if squeezed Study: no study specified.
Uric Acid	67%	78%	uric acid > 6 mg/dl in aymptomatic patients. Measuring levels in acute attacks is not recommended, as they can be normal. Note that cutoffs depend on gender and age. Study: Ann Rheum Dis. 2006 Oct;65(10):1301-11. PMID: 16707533