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Syncope

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Epilepsy: Sensitivity and Specificity

Introduction: aka seizure. See also Syncope as a differential diagnosis.

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Tags: Neurologic Tag this Diagnosis.

Differential Diagnoses include: Syncope

The sensitivity and specificity of findings for Epilepsy are listed below. See the left navigation bar to change the display.

Syncope

Finding SensitivitySpecificity Comments, Study
Abnormal Behavior Edit 92%67%

noted by bystanders

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Amnesia Edit 53%87%

i.e. does not recall behavior during event

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Chest Pain
Duplicate Edit
9.8%54.3%

ever

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Chest Pain
Duplicate Edit
2%87.2%

presyncopal

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Cut Tongue Edit 45%97%

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Cyanosis Edit 33%94%

observed by bystanders

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Head Turning Edit 43%97%

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

History of Coronary Artery Disease Edit 2%74.9%

(history of)

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Hypertension Edit 7.8%70.8%

physician-measured

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Limb Jerking Edit 69%88%

noted by bystanders

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Myalgia Edit 16%95%

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Palpitations Edit 3.9%66.2%

presyncopal

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Postictal Confusion Edit 94%69%

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Postictal Headache Edit 49%83%

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Presyncopal Diaphoresis Edit 5.9%65.3%

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Presyncopal Dyspnea Edit 2%76.3%

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Presyncopal Episodes
Duplicate Edit
27.5%27.4%

before actual syncope, by history

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Presyncopal Episodes
Duplicate Edit
23.5%13.7%

ever / of any type

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Presyncopal Nausea Edit 5.9%72.2%

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Presyncopal Warmth Edit 7.8%66.2%

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Presyncope with Heat Edit 7.8%73.1%

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Presyncope with Needle Edit 3.9%86.3%

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Presyncope with Standing Edit 5.9%67.6%

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Prodromal Deja Vu Edit 14%96%

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Prodromal Hallucinations Edit 8%98%

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Prodromal Preoccupation Edit 7.8%98.2%

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Prodromal Trembling Edit 29%94%

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Provoked by Stress Edit 57%85%

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Remembered Loss of Consciousness Edit 11.8%42.5%

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Self-Reported High Blood Pressure Edit 9.8%69%

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Syncope with Standing Edit 2%60%

(history of)

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Unresponsiveness Edit 77%75%

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Unusual Posturing Edit 35%97%

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Urinary Incontinence Edit 23%96%

aka "bedwetting"

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Vertigo Edit 5.9%78.5%

prodromal

Study: J Am Coll Cardiol. 2002 Jul 3;40(1):142-8. PMID: 12103268

Untagged

Finding SensitivitySpecificity Comments, Study
Elevated Prolactin Edit 46%96%

within 10-20min after event. This is for complex partial. Sensitivity up to 60% with generalized tonic-clonic.

Study: Neurology. 2005 Sep 13;65(5):668-75. PMID: 16157897

Interictal EEG
Duplicate Edit
29%99.5%

EEG findings are spikes or sharp waves, most often at the epileptogenic focus.

Sensitivity may be as high as 50% (depending on the study). Serial EEGs increase sensitivity up to 92% by 4 studies in one referenced case series.

Study: Epilepsia. 2006;47 Suppl 1:14-22. PMID: 17044820

Epilepsia. 1987 Jul-Aug;28(4):331-4. PMID: 3622408

Interictal EEG
Duplicate Edit
50%96%

Paper in Portuguese. Not read in full. Sensitivity 50-55%, upper limit of specificity 96%.

Study: Acta Med Port. 2004 Nov-Dec;17(6):465-70. Epub 2005 Jan 18. PMID: 16197858