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Disseminated Intravascular Coagulation: Sensitivity and Specificity

Introduction: None written.

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Tags: Hematologic Tag this Diagnosis.

Prevalence

Population / CalculatorPrevalence Comments / Study / Link
Septicemia 30% similar in gram positive and gram negative sepsis

Thromb Haemost. 1999 Aug;82(2):695-705. PMID: 10605770

Trauma 50% Thromb Haemost. 1999 Aug;82(2):695-705. PMID: 10605770
Acute Leukemia 15% Thromb Haemost. 1999 Aug;82(2):695-705. PMID: 10605770
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The sensitivity and specificity of findings for Disseminated Intravascular Coagulation are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %. Post-Test Probability (Predictive Value): %. Switch to display mode.
**Note that calculating probabilities from more than one finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)
Sensitive and Specific Findings
FindingResult SensitivitySpecificity
[ + ] ISTH Criteria + 0 - 91%97%
Sensitive Findings
FindingResult SensitivitySpecificity
[ + ] Elevated D-dimer Sensitivity = 93%
Poorly Diagnostic Findings
FindingResult SensitivitySpecificity
[ + ] Schistocytes Sensitivity = 50%
[ + ] Prolonged PT Sensitivity = 50%
[ + ] Prolonged PTT Sensitivity = 50%
[ + ] Decreased Fibrinogen Sensitivity = 28%