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Diabetic Ketoacidosis: Sensitivity and Specificity

Introduction: Acidemia from ketone production in a state of (at least functional) hypoinsulinemia and hyperglycemia. Much more common in type 1 Diabetes Mellitus.

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Tags: Endocrine Metabolic Tag this Diagnosis.

Prevalence

Population / CalculatorPrevalence Comments / Study / Link
Hyperglycemia and suspicious symptoms 14% patients presenting to the ED; glucose > 200 and either known diabetic + DKA-like symptoms or no diabetes diagnosis

Ann Emerg Med. 1999 Sep;34(3):342-6. PMID: 10459090

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The sensitivity and specificity of findings for Diabetic Ketoacidosis are listed below. See the left navigation bar to change the display.

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Finding SensitivitySpecificity Comments, Study
Abnormal Serum Bicarbonate Edit 84%99%

HCO3 < 15 mEq/l

Study: Ann Emerg Med. 1999 Sep;34(3):342-6. PMID: 10459090

Anion Gap Edit 92%85%

Study: Ann Emerg Med. 1999 Sep;34(3):342-6. PMID: 10459090

Urine Ketones Edit 99%69%

urine dipstick

Study: Ann Emerg Med. 1999 Sep;34(3):342-6. PMID: 10459090